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alpha Genes,TR

《英文msh詞典》alpha Genes,TR
[入口詞] alpha Genes,TR
[主題詞] Genes,erbA
[英文釋義] Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS,AVIAN),v-erbA. In cells,erbA genes encode thyroid hormone receptors (RECEPTORS,THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsivenss but not DNA binding capacity.

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